In Vitro Fertilization (IVF) is the laboratory fertilization when the woman eggs and sperm are joined in a laboratory dish. The word in vitro means outside the body. IVF involves the use of both and physical energy, time and money. There has been some the relationship between IVF and alcohol consumption. Research by American Fertility researchers has shown that drinking wine a week before IVF cycle reduces the chance of having a baby by more than 25%. This article analyzes in depth the relationship between alcohol and IVF.
To find out whether consuming alcohol at the beginning for an in vitro fertilization (IVF) affect the IVF outcomes, various researches have been performed. In one of the studies to learn about the effect of alcohol during IVF cycle, men and women were given self-administered questionnaires to complete before their IVF cycle. In the questionnaire captured the type of alcohol, frequency and the amount consumed.
Discrete survival analysis was then used to estimate the odds ratio at 95% confidence interval. The secondary outcomes were captured in different characteristics and point of failures such as failed fertilization, cycle cancellation, spontaneous abortion, and implantation failure. The different multicycle analysis was also conducted with different adjustment to capture various potential confounders such as cigarette use, cycle number, body mass index and age was conducted.
The number of couples who participated in the studies was 2545, but the total number of cycles that resulted is 4,730. Among the interviewed couples, about 41% women and 57% men took between 1 and six drinks per week. According to the studies, women who take at least 4 glasses of alcohol per week had 16% lower odds of resulting in a live birth rate as compared to those who took lesser drinks per week.
According to the studies, even the consumption of as low as 4 glasses of alcohol per week result in a lower IVF live birth rate. Although the effect of taking alcohol before fertility is not clearly defined, various researchers have stated that alcohol use during pregnancy is linked to the birth defect. The epidemiologic studies show that women who take the even higher amount of alcohol were more likely to be affected by infertility problems. Furthermore, women with moderate intake of alcohol do not show any increased during the pregnancy time. When it comes to alcohol type, women who consume wine tend to have shorter times to pregnancy as compared to another type of liquor.
Analysis of the studies:
The relationship between the consumption of alcohol among men and the infertility is not clear. While some studies have show that their lower fecundability with high consumption, others did not show any reduction the fertility rate with any amount or type of alcohol. Among women, every one drink added per day was associated with up to 13% lower oocytes. Moreover, those who took alcohol had a nonsignificantly decreased chance of pregnancy. The strongest association of alcohol and IVF was witnessed where the consumption of alcohol occurred in a very close time to the semen collection.
According to the studies, it is clear that alcohol during IVF stimulation has negative effects on fertility. However, although there is a large amount of analysis data on alcohol consumption on the fetus during pregnancy, there is only a little information on the relationship between IVF and alcohol. Moreover, most studies tend to assume that couples who undergo IVF cannot conceive without assistance and are unlikely to limit alcohol use before an IVF cycle, thinking that they will stop using it once they start taking the fertility drugs.
Surprisingly, although most of the couples taking the drinks have are aware that they are drinking too much, without hearing from the doctor, they are not willing to take any action. The research reveals that more men as compare to women take more than 4 drinks per week. Although most of the affected couples enjoy the drinks, most of them respond very positively when informed by a specialist to take a lesser amount of drinks per week. Female are advised to abstain completely from taking IVF treatment and alcohol especially after ovulation, which usually occurs on the 14th day of the 28-day cycles. It is highly recommended that women should never take alcohol during the IVF cycle. However, it might not be a bad idea for men.